If you want to disable secure boot and/or the caching feature of the SSD, of course you are free to do so. But this will require reinstalling the operating system. Not terribly hard.
However, if you want to use the SSD as a cache, then RAID is the required controller mode. It won't work otherwise. There have been many, many discussions in this forum as to how to set this up, which I won't repeat. Just do a search if you'd like more help.