The XPS 8500 motherboard works in a standard mATX case: the IO shield snaps in and the board mounting holes line up with the standoffs.
I seem to have the front panel wiring figured out: the power switch works for both on-off and the power light works. (I don't have a hard drive connected yet.) The Cooler Master case has a front USB 3.0 connector that matches up perfectly with the socket on the board, as is the case for the other connectors as well.