Can it be used on a windows 8 drive? I don't know anything about it so I can't say if it will work and preserve windows files. Remember that Win 8 reinstall disks don't come with new computers now. Make a repair boot disk in case you run into trouble. Win 8 computers usually come with Secure Boot so you might not be able to use the wipedrive cd. I would research this further before doing anything. Remove and reinstall does reformat the C drive.
Have you used all available tools to clean up the drive? Try reading and posting in the Virus Forum.